After speaking at the Wakanda Embassy, Black Panther fights Thanos and fends him off with the help of fellow Avengers Captain America, Thor, Iron Man, Hulk, and Black Widow. After regaining conscious, Thanos is approached by Erik Killmonger and Ulysses Klaue in a plot where they will obtain the Vibranium in Wakanda to empower Thanos. When Black Panther discovers this plot, he must work with Shuri, Okoye, and the Avengers to defeat them.

Ironheart, AKA Riri Williams (voiced by Sofia Wylie), who is having difficulty adjusting to college life as the youngest student there then the college's engineering lab is demolished by an alien and kidnaps her best friend. Inspired by Iron Man, she develops a plan to save her friend. The special will also feature appearances by Iron Man (voiced by Mick Wingert) and a new character named A.M.I. (voiced by Melanie Minichino).